12-Hydroxystearic acid

12-Hydroxystearic acid molecular structure
molecular structure · PubChem
AKA: 12-HYDROXYOCTADECANOIC ACID, 106-14-9, DL-12-Hydroxystearic acid, Cerit Fac 3, Hydrofol acid 200, Ceroxin GL, Barolub FTO, Loxiol G 21
Plant-Derived
Skin Conditioner
Acid
Not Clean
12-hydroxyoctadecanoic acid is a hydroxy fatty acid that is stearic acid bearing a hydroxy substituent at position 12. It has a role as a plant metabolite and a bacterial xenobiotic metabolite. It is a hydroxyoctadecanoic acid and a secondary alcohol. It is a conjugate acid of a 12-hydroxyoctadecanoate.
Solubility Soluble in alcohol, ether, chloroform; insoluble in water
Mol. Weight
300.50
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Amended Final Report on the Safety Assessment of Hydroxystearic Acid
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
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Final Report on the Safety Assessment of Isostearic Acid
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
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Final Report on the Safety Assessment of Oleic Acid, Lauric Acid, Palmitic Acid, Myristic Acid, and Stearic Acid
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
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Final Report: Safety Assessment of Polyhydroxystearic Acid, Poly(3-Hydroxyoctanoic Acid, and Polylactic Acid as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
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Re-evaluation: Safety Assessment of Hydroxystearic Acid as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
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10-Hydroxystearic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
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Polyhydroxystearic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
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Stearic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Hydroxystearic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
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Isostearic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Polyhydroxystearic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Stearic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Simultaneous contact sensitivity to hydroxystearic acid and C18-36 acid triglyceride in lip glosses.
Kimura M, Kawada A, Ogino M, Murayama Y
Contact dermatitis, 2002
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Microemulsions based on TPGS and isostearic acid for imiquimod formulation and skin delivery.
Pescina S, Garrastazu G, Del Favero E, Rondelli V, Cantù L et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2018
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Bio-derived hydroxystearic acid ameliorates skin age spots and conspicuous pores.
Schütz R, Rawlings AV, Wandeler E, Jackson E, Trevisan S et al.
International journal of cosmetic science, 2019
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Bio-derived hydroxystearic acid ameliorates skin age spots and conspicuous pores.
Schütz R, Rawlings AV, Wandeler E, Jackson E, Trevisan S et al.
International journal of cosmetic science, 2019
→
Bio-derived hydroxystearic acid ameliorates skin age spots and conspicuous pores.
Schütz R, Rawlings AV, Wandeler E, Jackson E, Trevisan S et al.
International journal of cosmetic science, 2019
→
Verified Jun 2026
Data: PubChem · CosIng