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Ceramide np (N-acylated Phytosphingosine)
AKA “N-Acylated Phytosphingosine”
Ingredient
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Ingredient Facts
Ceramide np (N-acylated Phytosphingosine)
Ingredient · Hair Conditioning · EWG: 4
Synthetic
Skin Conditioner
Hair Care
Ceramide
Not Clean
Ceramide NP (N-Acylated Phytosphingosine) is a cosmetic ingredient used as hair conditioning, skin conditioning.
CAS #
72968-43-5
Form
Liquid
See origin →
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Strengthens skin barrier
Locks in moisture
Prevents moisture loss
Traditional Use
Developed in the 1990s as a synthetic ceramide designed to mimic natural ceramides found in skin barrier lipids. Ceramides were identified as key components of the stratum corneum, and synthetic versions were created to repair compromised skin barriers and reduce transepidermal water loss.
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Balance + Support Duo
Marie Veronique
 →
The New Tendency Complete Set
Nécessaire
 →
Black Tulip Facial Treatment
Bloom Effects
 →
calm & clarify duo
Cocokind
 →
ceramide hydration duo
Cocokind
 →
ceramide lip blur balm
Cocokind
 →
travel-size Electrolyte Water Cream
Cocokind
 →
electrolyte water cream
Cocokind
 →
Gentle Body Wash - Unscented
Kinship
 →
Gentle Genius™ Barrier Care Rapid Rescue Hand Cream
Pai Skincare
 →
The Hand Cream + The Tube Key
Nécessaire
 →
hydration heroes set
Cocokind
 →
Hydration Set
Kinship
 →
milky-soft face and body cleanser
Cocokind
 →
Moisturizing Body Cream - Unscented
Kinship
 →
Moisturizing Body Cream - Vanilla
Kinship
 →
Morning + Night Serum Set
Kinship
 →
The New Tendency Duo
Nécessaire
 →
flavored ceramide lip blur balm
Cocokind
 →
peptide fine line eye gel
Cocokind
 →
Restorative Body Serum - Unscented
Kinship
 →
Restorative Body Serum - Vanilla
Kinship
 →
retinol face + body duo
Cocokind
 →
rise + shine trio
Cocokind
 →
Royal Tulip Vitamin C Facial Oil
Bloom Effects
 →
Mini Barrier Repair Cream
Alpyn Beauty
 →
Instant Bright Eye
Alpyn Beauty
 →
Barrier Repair Cream
Alpyn Beauty
 →
Daily Vitamin Infusion
Indie Lee
 →
Barrier Lipid Complex
Marie Veronique
 →
Barrier Restore Serum
Marie Veronique
 →
Gentle Retinol Night Serum
Marie Veronique
 →
Supernutrient Firming Facial
Marie Veronique
 →
Vitamins C+E+Ferulic Serum
Marie Veronique
 →
Superkind Bio-Barrier Eye Crème
Tata Harper Skincare
 →
Superkind Bio-Barrier Serum
Tata Harper Skincare
 →
Alpine Rich Cream | Dry Skin's Dream Come True – Ursa Major Skincare
Ursa Major
 →
Skin Activator Packette
Credo Beauty
 →
Skin Activator Serum
Credo Beauty
 →
Ceramide Refillable Lip Silk
SOSHE Beauty
 →
Easy Calm, Easy Glow Gift Set
Pai Skincare
 →
Super Rich Ceramide + Collagen Firming Cream
Kinship
 →
Take Your Vitamins Duo
Indie Lee
 →
The Body Brush
Nécessaire
 →
The Body Duo
Nécessaire
 →
The Body Serum | 0.5% Hyaluronic Acid | Travel
Nécessaire
 →
The Bodycare Ritual - Unscented
Kinship
 →
The Bodycare Ritual - Vanilla
Kinship
 →
Glow + Go Set
Kinship
 →
The Hand Duo
Nécessaire
 →
Ceramide Np
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Ceramide NP (N-Acylated Phytosphingosine)
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Ceramide Np
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
The Design and Optimization of Ceramide NP-Loaded Liposomes to Restore the Skin Barrier.
Şahin Bektay H, Sağıroğlu AA, Bozali K, Güler EM, Güngör S
Pharmaceutics, 2023
→
The Effectiveness and Safety of a Skin Care Product With Centella asiatica Leaf Extract, Ceramide NP, and Panthenol in Subjects With Sensitive Skin: A
Su Z, Zheng Y, Yi J, Lai W, Ye C
Journal of cosmetic dermatology, 2025
→
The Effectiveness and Safety of a Skin Care Product With Centella asiatica Leaf Extract, Ceramide NP, and Panthenol in Subjects With Sensitive Skin: A
Su Z, Zheng Y, Yi J, Lai W, Ye C
Journal of cosmetic dermatology, 2025
→
Verified Jun 2026
Data: CosIng · EWG · CIR