SUBSTITUTED
molecular structure · PubChem
Synthetic
Skin Conditioner
Not Clean
SUBSTITUTED is a cosmetic ingredient.
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Final Report: Safety Assessment of Dimethicones, Methicone and Substituted-Methicone Polymers as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report: Safety Assessment of Linear Phenyl-Substituted Methicones as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Growth inhibition of human melanoma tumor cells by the combination of sodium phenylacetate (NaPA) and substituted dextrans and one NaPA-dextran conjug
Gervelas C, Avramoglou T, Crépin M, Jozefonvicz J
Anti-cancer drugs, 2002
Verified Jun 2026
Data: CosIng