Contact allergy caused by methyli…n-French experience.

Between 2010-2013, contact allergy to methylisothiazolinone (MI), a preservative used in cosmetics and household products, spiked dramatically in Europe—reaching 6-7% of dermatology patients tested. The majority of cases were middle-aged women with facial and hand rashes, though young children were also affected. This happened even though MI was deemed 'safe' at concentrations up to 100ppm, suggesting the approved limit wasn't actually safe for widespread use.