Lack of binding to isolated estro…tive and Tinosorb S.

🔬 Peer-reviewed

Lack of binding to isolated estrogen or androgen receptors, and inactivity in the immature rat uterotrophic assay, of the ultraviolet sunscreen filters Tinosorb M-active and Tinosorb S.

J Ashby, H Tinwell, J Plautz, K Twomey, P A Lefevre

Regulatory toxicology and pharmacology : RTP · 2001

Findings

Tinosorb M-active and Tinosorb S showed no signs of mimicking estrogen or androgen hormones in lab tests or in live animal studies. This is reassuring because some other sunscreen filters have shown hormone-like activity, but these two didn't bind to hormone receptors or trigger estrogenic responses.

Design

Review

Evidence

Moderate

Journal

Regulatory toxicology and pharmacology : RTP