Leg cramps (systremma0 and "restl…amin E (tocopherol).
🔬 Peer-reviewed
Leg cramps (systremma0 and "restless legs" syndrome. Response to vitamin E (tocopherol).
S Ayres, R Mihan
California medicine · 1969
Findings
In a small clinical study, 24 patients with frequent nighttime leg cramps experienced significant relief after taking 100 IU of vitamin E (d-alpha-tocopheryl acetate) three times daily before meals. Two patients with restless legs syndrome also saw improvement, and one patient's severe nighttime rectal cramps resolved as well.
Design
Cohort
Evidence
Moderate
Journal
California medicine