Efficacy and safety of a 12-month…r oral isotretinoin.

🔬 Peer-reviewed

Efficacy and safety of a 12-month treatment with a combination of hydroxypinacolone retinoate and retinol glycospheres as maintenance therapy in acne patients after oral isotretinoin.

Vincenzo Bettoli, Stefania Zauli, Alessandro Borghi, Giulia Toni, Michela Ricci, Alberto M Bertoldi + 1 more

Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia · 2017

Findings

In a small study of 39 acne patients, a gel combining hydroxypinacolone retinoate and encapsulated retinol prevented acne relapse in 85% of people over 12 months after they stopped taking oral isotretinoin (a heavy-duty acne drug). No serious side effects were reported, though this was a limited trial focused on maintenance rather than treating active acne.

Design

Clinical Trial

Sample

n=6

Evidence

Moderate

Journal

Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia