Keratin 6A promotes skin inflamma…on in keratinocytes.

Keratin 6A (KRT6A) — a protein your skin naturally makes — actually triggers inflammation when your skin barrier is damaged, making conditions like rosacea and psoriasis worse. In animal and cell studies, turning down KRT6A reduced inflammation significantly, while increasing it made inflammation worse. This suggests KRT6A might be a new target for treating inflammatory skin diseases.