A Cohort Clinical Study on the Ef…atitis of the Scalp.
🔬 Peer-reviewed
A Cohort Clinical Study on the Efficacy of Topical Salicylic Acid/Piroctone Olamine Dandruff Pre-Gel and Cleanser in Improving Symptoms of Moderate to Severe Seborrheic Dermatitis of the Scalp.
Ling Ge, Zhiqing Liu, Shanhua Xu, Chuying Li, Meitong Jin, Yinli Luo + 10 more
Journal of cosmetic dermatology · 2025
Findings
In a 4-week study of 20 people with moderate to severe scalp dandruff and seborrheic dermatitis, piroctone olamine combined with salicylic acid significantly reduced dandruff (55% improvement), itching (53% improvement), and scalp greasiness (46% improvement). After 16 weeks of maintenance treatment, 90% of participants saw their severe cases improve to mild, with an overall 80% clinical improvement rate.
Design
Review
Sample
n=20
Evidence
Moderate
Journal
Journal of cosmetic dermatology