An Open Label Clinical Trial to E…damaged Facial Skin.

🔬 Peer-reviewed

An Open Label Clinical Trial to Evaluate the Efficacy and Tolerance of a Retinol and Vitamin C Facial Regimen in Women With Mild-to-Moderate Hyperpigmentation and Photodamaged Facial Skin.

James H Herndon, Lily I Jiang, Tatiana Kononov, Theresa Fox

Journal of drugs in dermatology : JDD · 2016

Findings

After 12 weeks, this retinol and vitamin C combo visibly improved hyperpigmentation and sun damage in 44 women—with most improvements showing up by week 8. The trade-off: expect dryness in weeks 1-2, but it went away by week 12. The encapsulated retinol formulation (0.5%) paired with 30% vitamin C actually delivered measurable results.

Design

Clinical Trial

Evidence

Moderate

Journal

Journal of drugs in dermatology : JDD