Multifunctional carbomer based fe…NLRP3 inflammasome.

🔬 Peer-reviewed
Multifunctional carbomer based ferulic acid hydrogel promotes wound healing in radiation-induced skin injury by inactivating NLRP3 inflammasome.
Congshu Huang, Chaoji Huangfu, Zhijie Bai, Long Zhu, Pan Shen, Ningning Wang + 5 more
Journal of nanobiotechnology · 2024
Findings

Researchers created a ferulic acid hydrogel (a topical gel formulation) and tested it on radiation-damaged skin in the lab and in animal models. The 10% concentration version performed best, significantly reducing inflammation and oxidative stress while promoting skin healing, collagen rebuilding, and blood flow recovery compared to untreated radiation injuries.

Design
Review
Evidence
Moderate
Journal
Journal of nanobiotechnology