Multifunctional fucoidan-loaded Z…ected wound healing.
🔬 Peer-reviewed
Multifunctional fucoidan-loaded Zn-MOF-encapsulated microneedles for MRSA-infected wound healing.
Zichao Jiang, Jingyi Li, Jiahao Wang, Yixiao Pan, Shuailong Liang, Yihe Hu + 1 more
Journal of nanobiotechnology · 2024
Findings
Researchers created a microneedle patch loaded with fucoidan (a seaweed extract) that penetrated deep into skin to fight MRSA infections in mice. The patch delivered zinc ions and hyaluronic acid alongside the fucoidan, which worked together to kill bacteria, reduce inflammation, and speed up wound healing—targeting bacteria even inside cells where antibiotics typically can't reach.
Design
Cohort
Evidence
Moderate
Journal
Journal of nanobiotechnology