Multifunctional fucoidan-loaded Z…ected wound healing.
🔬 Peer-reviewed
Multifunctional fucoidan-loaded Zn-MOF-encapsulated microneedles for MRSA-infected wound healing.
Zichao Jiang, Jingyi Li, Jiahao Wang, Yixiao Pan, Shuailong Liang, Yihe Hu + 1 more
Journal of nanobiotechnology · 2024
Findings
Researchers created microneedle patches loaded with fucoidan (a seaweed extract) that can penetrate skin and deliver antibacterial compounds directly to infected wound tissue. In mouse studies, these patches successfully targeted drug-resistant MRSA bacteria hiding inside cells, reduced inflammation, and promoted wound healing—addressing three major problems that make infected wounds hard to treat.
Design
Cohort
Evidence
Moderate
Journal
Journal of nanobiotechnology