Multifunctional fucoidan-loaded Z…ected wound healing.
🔬 Peer-reviewed
Multifunctional fucoidan-loaded Zn-MOF-encapsulated microneedles for MRSA-infected wound healing.
Zichao Jiang, Jingyi Li, Jiahao Wang, Yixiao Pan, Shuailong Liang, Yihe Hu + 1 more
Journal of nanobiotechnology · 2024
Findings
Researchers created a microneedle patch infused with fucoidan (a seaweed extract) and zinc nanoparticles to treat infected wounds caused by drug-resistant bacteria (MRSA). In mouse studies, the patches successfully penetrated skin, delivered the active ingredients deep into the wound layer, killed bacteria, reduced inflammation, and promoted healing—all without systemic antibiotics.
Design
Cohort
Evidence
Moderate
Journal
Journal of nanobiotechnology