Hydroxyisohexyl 3-cyclohexene car…fragrance allergen.

Findings

Lyral, a common fragrance ingredient, triggered allergic reactions in 89% of people who were already sensitized to it—even at the low doses typically used in cosmetic products. The study found that 2-3% of eczema patients react to Lyral, and researchers concluded current usage levels are causing new sensitization in the general population. They recommended significantly reducing how much Lyral brands are allowed to use.

Design
Cohort
Evidence
Moderate
Journal
Contact dermatitis