Hydroxyisohexyl 3-cyclohexene car…fragrance allergen.
🔬 Peer-reviewed
Hydroxyisohexyl 3-cyclohexene carboxaldehyde- known as Lyral: quantitative aspects and risk assessment of an important fragrance allergen.
J D Johansen, P J Frosch, C Svedman, K E Andersen, M Bruze, C Pirker + 1 more
Contact dermatitis · 2003
Findings
Lyral, a common fragrance ingredient, triggered allergic reactions in 89% of people who were already sensitized to it—even at the low doses typically used in cosmetic products. The study found that 2-3% of eczema patients react to Lyral, and researchers concluded current usage levels are causing new sensitization in the general population. They recommended significantly reducing how much Lyral brands are allowed to use.
Design
Cohort
Evidence
Moderate
Journal
Contact dermatitis