Safety assessment of cyclomethico…cycloheptasiloxane.

🛡️ Safety-assessed
Safety assessment of cyclomethicone, cyclotetrasiloxane, cyclopentasiloxane, cyclohexasiloxane, and cycloheptasiloxane.
Wilbur Johnson, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen, Daniel C Liebler + 5 more
International journal of toxicology · 2011
Findings

Cyclopentasiloxane and related siloxanes showed minimal absorption through skin and no signs of irritation or allergic reactions in testing. The researchers concluded these ingredients are safe at typical use levels in cosmetics, with minimal risk of systemic exposure from skincare products.

Design
Review
Evidence
Moderate
Journal
International journal of toxicology