Retinyl retinoate, a novel hybrid…ed-controlled trial.
🔬 Peer-reviewed
Retinyl retinoate, a novel hybrid vitamin derivative, improves photoaged skin: a double-blind, randomized-controlled trial.
H Kim, J Koh, J Baek, Y Seo, B Kim, J Kim + 3 more
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2011
Findings
In a 12-week trial, retinyl retinoate (a gentler retinoid hybrid) reduced wrinkle depth and roughness 22% more effectively than standard retinol, with visible improvements showing up in as little as 4 weeks. The ingredient was designed to be less irritating and more stable than traditional retinoids, addressing two major complaints about retinol.
Design
Randomized Controlled Trial
Evidence
Strong
Journal
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)