Evidence for chemical and cellula…ormaldehyde release.
🔬 Peer-reviewed
Evidence for chemical and cellular reactivities of the formaldehyde releaser bronopol, independent of formaldehyde release.
Mustapha Kireche, Jean-Luc Peiffer, Diane Antonios, Isabelle Fabre, Elena Giménez-Arnau, Marc Pallardy + 2 more
Chemical research in toxicology · 2011
Findings
Bronopol, a preservative marketed as a formaldehyde releaser, doesn't actually work the way we thought. Researchers found it releases very little formaldehyde but instead breaks down into other reactive molecules (like 2-bromoethanol) that trigger immune responses in skin cells at much lower concentrations than formaldehyde alone would. This means bronopol can cause allergic reactions through its own chemical activity, not just from the formaldehyde it releases.
Design
Cohort
Evidence
Moderate
Journal
Chemical research in toxicology