Novel nanocapsule of α-lipoic aci…topical application.

🔬 Peer-reviewed

Novel nanocapsule of α-lipoic acid reveals pigmentation improvement: α-Lipoic acid stimulates the proliferation and differentiation of keratinocyte in murine skin by topical application.

Yoshiki Kubota, Mina Musashi, Teruaki Nagasawa, Nanako Shimura, Rie Igarashi, Yoko Yamaguchi

Experimental dermatology · 2019

Findings

When alpha-lipoic acid was wrapped in tiny nanoparticles (8-15 nanometers) to help it penetrate skin better, it reduced UV-induced dark spots and thickened the epidermis in mouse skin. The improvement came specifically from the alpha-lipoic acid itself, not from the encapsulation materials used.

Design

Review

Evidence

Moderate

Journal

Experimental dermatology