Final report on the safety assess…30-45 alkyl methicon

Findings

Dimethicone and related silicones weren't absorbed through skin or absorbed orally, showed minimal irritation in rabbit and human tests, and didn't cause allergic reactions at concentrations up to 5%. No reproductive or developmental toxicity was found in rats, rabbits, and monkeys at doses tested, though one study noted decreased body weight in treated males.

Design
Review
Evidence
Moderate
Journal
International journal of toxicology