Efficacy of combined treatment wi…d, split-face study.

🔬 Peer-reviewed

Efficacy of combined treatment with human adipose tissue stem cell-derived exosome-containing solution and microneedling for facial skin aging: A 12-week prospective, randomized, split-face study.

Gyeong-Hun Park, Hyuck Hoon Kwon, Joon Seok, Steven Hoseong Yang, Joon Lee, Byung Chul Park + 2 more

Journal of cosmetic dermatology · 2023

Findings

When exosome solution (derived from fat stem cells) was applied with microneedling to one side of people's faces, that side showed measurably better improvements in wrinkles, skin elasticity, hydration, and pigmentation compared to the control side treated with saline alone. Results were tracked over 12 weeks with objective measurements and tissue analysis, with no serious side effects reported.

Design

Randomized Controlled Trial

Evidence

Strong

Journal

Journal of cosmetic dermatology