Efficacy of an agonist of α-MSH,…n hair pigmentation.
🔬 Peer-reviewed
Efficacy of an agonist of α-MSH, the palmitoyl tetrapeptide-20, in hair pigmentation.
S Almeida Scalvino, A Chapelle, N Hajem, E Lati, P Gasser, J-C Choulot + 5 more
International journal of cosmetic science · 2018
Findings
A lab-created peptide called palmitoyl tetrapeptide-20 (PTP20) showed promise in preventing hair greying by boosting melanin production and reducing oxidative stress in hair follicles. In a small 3-month trial on 15 men with premature greying, daily application of a lotion containing PTP20 increased expression of melanin-producing proteins in plucked hairs.
Design
Review
Evidence
Moderate
Journal
International journal of cosmetic science