Efficacy of an agonist of α-MSH,…n hair pigmentation.

Findings

A lab-created peptide called palmitoyl tetrapeptide-20 (PTP20) showed promise in preventing hair greying by boosting melanin production and reducing oxidative stress in hair follicles. In a small 3-month trial on 15 men with premature greying, daily application of a lotion containing PTP20 increased expression of melanin-producing proteins in plucked hairs.

Design
Review
Evidence
Moderate
Journal
International journal of cosmetic science