Efficacy and Safety of Poly-l-Lac…A Systematic Review.
🔬 Peer-reviewed
Efficacy and Safety of Poly-l-Lactic Acid in Facial Aesthetics: A Systematic Review.
Roberta Signori, Antony de Paula Barbosa, Fernando Cezar-Dos-Santos, Ana Claudia Carbone, Silvio Ventura, Bryanne Brissian de Souza Nobre + 4 more
Polymers · 2024
Findings
PLLA showed real results in clinical trials—it thickened skin and improved facial volume loss, with effects lasting at least 25 months. It performed better than collagen and hydrogel comparisons. But here's the catch: the overall evidence quality is low, and side effects like bruising, nodules, and swelling happened in most studies.
Design
Systematic Review
Evidence
Strong
Journal
Polymers
Ingredients studied