Hexapeptide-11 is a novel modulat…diploid fibroblasts.
🔬 Peer-reviewed
Hexapeptide-11 is a novel modulator of the proteostasis network in human diploid fibroblasts.
Aimilia D Sklirou, Marianna Ralli, Maria Dominguez, Issidora Papassideri, Alexios-Leandros Skaltsounis, Ioannis P Trougakos
Redox biology · 2015
Findings
In lab tests on human skin cells, Hexapeptide-11 activated the cell's natural cleanup and protection systems (proteasome, autophagy, antioxidants) without toxicity. In human subjects, it improved skin elasticity—though the study didn't measure wrinkles or other visible aging signs directly.
Design
Review
Evidence
Moderate
Journal
Redox biology
Ingredients studied