Anti-inflammatory effects of phyt…and MAPK mechanism.
🔬 Peer-reviewed
Anti-inflammatory effects of phytosphingosine-regulated cytokines and NF-kB and MAPK mechanism.
Mikyung Sung, Sojung Lim, Seungwon Park, Yongjin Choi, Sangchul Kim
Cellular and molecular biology (Noisy-le-Grand, France) · 2024
Findings
Phytosphingosine (PHS) reduced multiple inflammatory markers in skin cells, including IL-6, IL-8, and nitric oxide production. It works by blocking two major inflammatory pathways (NF-κB and MAPK) that trigger skin inflammation—think of it as turning down the volume on your skin's inflammatory response rather than muting it completely.
Design
Review
Evidence
Moderate
Journal
Cellular and molecular biology (Noisy-le-Grand, France)
Ingredients studied