Phytic Acid Improves the Skin Bar…le-3-Propionic Acid.

🔬 Peer-reviewed
Phytic Acid Improves the Skin Barrier Function in Murine Models of Atopic Dermatitis Through Skin Microbiota-Derived Indole-3-Propionic Acid.
Piao Wang, Lan Yang, Lu Chen, Xinyu Huang, Zhen Lin, Yue Li + 8 more
Allergy · 2025
Findings

Phytic acid (a compound found in high-fiber foods) improved skin barrier function in mice with atopic dermatitis when taken orally or applied topically. It worked by reshaping the skin's microbiota to produce more of a metabolite called indole-3-propionic acid, which strengthened the skin's protective barrier.

Design
Review
Evidence
Moderate
Journal
Allergy
Ingredients studied