Topical Application of Centella a…d Clinical Efficacy.

Centella asiatica (gotu kola) contains compounds like asiaticoside and madecassoside that boost collagen production, reduce inflammation, and protect skin from oxidative stress. When delivered through advanced formulas like hydrogels and nanostructures, it showed measurable improvements in wound healing speed and size reduction across multiple wound types, including diabetic ulcers and burns—though specific healing timelines weren't detailed in this review.