Efficacy and Safety of Topical Co…reatment of Rosacea.
🔬 Peer-reviewed
Efficacy and Safety of Topical Compound Heparin Sodium Allantoin Gel (Main Components: Onion Extract Quercetin) for the Treatment of Rosacea.
Zining Xu, Biao Yu, Yuxin Qing, Shuhong Ye, Bingyang Xu, Yuanqin Wang + 4 more
Journal of cosmetic dermatology · 2025
Findings
In an 82-person trial, a gel containing allantoin, heparin sodium, and onion extract reduced rosacea redness, burning, and itching better than standard treatments over 12 weeks. It also strengthened the skin barrier by improving hydration and reducing water loss—especially for people with demodex mites.
Design
Randomized Controlled Trial
Evidence
Strong
Journal
Journal of cosmetic dermatology