Aspalathin, a key flavonoid in ro…n atopic dermatitis.

In mice with atopic dermatitis, aspalathin (a compound that makes up over 40% of green rooibos) reduced redness, scaling, and skin thickening when applied topically. It also lowered inflammation markers and immune response signals both in the skin and throughout the body, including reducing allergy-related antibodies (IgE and IgG2a) in the bloodstream.