Efficacy and safety of bromelain:…w and meta-analysis.

Bromelain—an enzyme from pineapple—showed modest pain relief when taken orally (about 0.27 points better than placebo on pain scales), and was more effective for sinusitis than other conditions. When applied topically to wounds, it significantly sped up healing by nearly 7 days. Don't expect dramatic results, but side effects were generally mild (bloating, nausea, headache).