Bromelain

AKA: Pineapple protease, Bromelin
Synthetic
Rx Active
Skin Conditioner
Enzyme
Clean
Bromelain is a mixture of enzymes found in pineapple juice
CAS #
9001-00-7, 37189-34-7
Form
Powder
Functions
Keratolytic
A pharmaceutical-grade active. These are the heavy hitters — often prescription-strength or regulated for potency.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Supports cell turnover
Unclogs pores
Traditional Use
Extracted from pineapple plants used in tropical regions. Discovered as an enzyme in the 1870s, bromelain was adopted by the cosmetics industry in the late 20th century as a natural exfoliant and anti-inflammatory agent for skincare.
EWG
2
CIR
Insufficient
Pregnancy
Caution
CIR Safety Findings
ewg-2
pregnancy-nursing-safe
all-shades-safe
Regulatory Status
USAunder review
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types, gentle
Best For
Uneven Texture
Pregnancy & Breastfeeding Safe
Caution
The paper trail
🔬Peer-reviewed1 paper
⚖️Regulatory1 listing
🛡️Safety-assessed1 review
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: CosIng · EWG · CIR