Immune response to topical sodium…contact dermatitis.

🔬 Peer-reviewed

Immune response to topical sodium lauryl sulfate differs from classical irritant and allergic contact dermatitis.

Marvin Nüsken, Fabian Heinemeier, Silke Sabina Matzke, Patryk Porebski, Susann Forkel, Prasad Dasari + 4 more

European journal of immunology · 2024

Ingredients studied

Sodium Lauryl Sulfate →

Findings

Sodium lauryl sulfate (SLS) causes skin reactions differently than typical allergens or irritants—it triggers more skin cell growth than immune cell activity. Interestingly, up to 20% of people react to SLS in patch tests, but the reaction doesn't involve the classical allergic or irritant pathways researchers expected.

Design

Review

Evidence

Moderate

Journal

European journal of immunology