The efficacy of hyaluronic acid f…histological study.
🔬 Peer-reviewed
The efficacy of hyaluronic acid fragments with amino acid in combating facial skin aging: an ultrasound and histological study.
Antonio Scarano, E Qorri, A Sbarbati, S A Gehrke, Alessio Frisone, D Amuso + 1 more
Journal of ultrasound · 2024
Findings
When injected into the skin, low molecular weight hyaluronic acid combined with amino acids boosted collagen production, increased blood vessel formation, and thickened the epidermis in 20 women over 3 months. However, ultrasound measurements showed no statistically significant change in overall skin thickness—meaning the microscopic improvements didn't translate to measurable thickness gains that imaging could detect.
Design
Review
Evidence
Moderate
Journal
Journal of ultrasound
Ingredients studied