murphy1,5-Pentanediol
AKA: Pentane-1, 5-diol, 111-29-5, 5-Dihydroxypentane, Pentamethylene glycol, 5-Pentamethylene glycol, 5-Pentylene glycol, Alpha, Omega-Pentanediol
Synthetic
Humectant
Solvent
Synthetic
Clean
OriginSynthesized from petroleum-derived hydrocarbons or produced through fermentation of sugars via microbial processes. Manufactured by catalytic hydrogenation or chemical synthesis to create the five-carbon diol compound.
Pentane-1,5-diol is a primary alcohol.
Solubility Miscible with water
Formula
C5H12O2
Mol. Weight
104.15
CAS #
111-29-5
Form
Liquid
State
Liquid
Skin Types
●all-skin-types
Best For
General
Functions
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Dissolves Ingredients
Dissolves other ingredients
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory0 listings
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Insufficient
Pregnancy
—
CIR Safety Findings
Not Phototoxic
Human test found no phototoxicity in the CIR safety assessment (CIR 731)
Not a Skin Irritant
4 studies / 4 not irritating (CIR 731)
Not a Sensitizer
3 studies / 3 not sensitizing / plus 1 case report (CIR 731)
Mixed Eye Irritation Results
1 study / 1 mixed / reactions mild (CIR 731)
Concentration Guide
CIR lists it as not reported to be in use.
CIR · report published 2024
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR