murphy1-Naphthol
AKA: 90-15-3, Naphthalen-1-ol, Alpha-naphthol, 1-Naphthalenol, 1-Hydroxynaphthalene, Furro ER, Ursol ERN, Fouramine ERN, Fourrine ERN
Synthetic
Not Clean
Origin1-Naphthol is synthesized from naphthalene, a polycyclic aromatic hydrocarbon derived from coal tar or petroleum refining.
It is produced through hydroxylation of naphthalene using catalytic oxidation or sulfonation followed by alkaline fusion processes.
1-naphthol (1N) is a metabolite of carbaryl and naphthalene that is an intermediate in Metabolism of xenobiotics by cytochrome P450. It is generated by spontaneous reaction from (1R,2S)-Naphthalene epoxide then is it converted to 1,4-Dihydroxynaphthalene. Although 1-Naphthol is not persistent in the body, a single urine sample may adequately predict exposure over several months to chlorpyrifos, which is a broad-spectrum organophosphate insecticide. In adult men, TCPY and 1N were associated with reduced testosterone levels (A3198, A3199).
Solubility In water, 866 mg/L at 25 °C
Formula
C10H8O
Mol. Weight
144.17
CAS #
90-15-3
Form
Powder
State
Pellets or Large Crystals
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
No
Functions
Hair Dyeing
Reduces Inflammation
Colors Hair
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
8
CIR
Safe as used
Pregnancy
No
CIR Safety Findings
Not a Sensitizer
2 studies / 2 not sensitizing / plus 1 case report (CIR 147)
Eye Irritant in Testing
3 studies / 3 irritating / reactions severe (CIR 147)
Mixed Skin Irritation Results
4 studies / 2 irritating / 1 mixed / 1 not irritating / reactions moderate to severe (CIR 147)
Dermal Absorption 14–21%
2 results from in vitro tests in the CIR safety assessment (CIR 147)
Regulatory Agencies
🧂Conflict of interest.
Verified Jun 2026 · 🧪 = conflict
Data: PubChem · CosIng · EWG · CIR