2-Amino-6-Chloro-4-Nitrophenol

AKA: 6358-09-4, 6-Chloro-4-nitro-2-aminophenol, RODOL 9R BASE, COLOREX 2A6C4NP
Synthetic
Not Clean
OriginSynthesized from nitro-substituted chlorobenzene derivatives through multi-step organic chemistry reactions. Produced via nitration, chlorination, and amino group introduction of phenolic precursors.
2-amino-6-chloro-4-nitrophenol
Formula
C6H5ClN2O3
Mol. Weight
188.57
CAS #
6358-09-4
Form
Powder
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
No
Functions
Hair Dyeing
Colors Hair
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
6
CIR
Safe as used
Pregnancy
No
CIR Safety Findings
Not a Skin Irritant
1 study / 1 not irritating (CIR 59)
Not a Sensitizer
1 study / 1 not sensitizing (CIR 59)
Eye Irritant in Testing
1 study / 1 irritating (CIR 59)
Dermal Absorption 0.189–1.213%
3 results from animal tests in the CIR safety assessment (CIR 59)
Concentration Guide
0%50%100%
Reg. limit 2%
CIR lists it as not reported to be in use.
CIR · report published 2017
EU regulatory limit: 2.0%. (a) To be printed on the label: The mixing ratio. ‘ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of... Source: EU Cosmetics Regulation (EC) 1223/2009, Annex III (Restricted Substances), Entry 252.
Regulatory Status
USA✔ permitted
EU✔ permitted
JAPAN✔ permitted
CANADA✔ permitted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR