2-Nitro-p-Phenylenediamine

AKA: 2-Nitro-4-phenylenediamine, 5307-14-2, 2-nitrobenzene-1, 4-diamine, 2-Nitro-1, 4-phenylenediamine, 1, 4-Diamino-2-nitrobenzene, 4-Benzenediamine, 5-Diaminonitrobenzene, 4-benzenediamine
Synthetic
Not Clean
OriginSynthesized from p-phenylenediamine through nitration with nitric acid or similar nitrating agents. The resulting compound is produced via selective nitration at the para position of the aromatic ring.
2-Nitro-p-phenylenediamine (CI 76070)
Solubility less than 1 mg/mL at 72 °F (NTP, 1992)
Formula
C6H7N3O2
Mol. Weight
153.14
CAS #
5307-14-2
Form
Liquid
State
Almost black needles with dark-green luster or black powder. (NTP, 1992)
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
No
Allergen Warning
⚠️ PPD (Hair Dye)
Functions
Hair Dyeing
Antioxidant Protection
Reduces Inflammation
Fights Bacteria
Colors Hair
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory0 listings
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
6
CIR
Insufficient data
Pregnancy
No
CIR Safety Findings
Not a Skin Irritant
1 study / 1 not irritating (CIR 198)
Mixed Eye Irritation Results
2 studies / 1 irritating / 1 mixed / reactions slight to mild (CIR 198 and 932)
Sensitizer in Testing
1 study / 1 sensitizing / plus 6 case reports (CIR 198 and 932)
Dermal Absorption 0.04–29%
6 results from animal / human tests in the CIR safety assessment (CIR 198 and 932)
Concentration Guide
CIR's newest survey reports no concentration of use.
CIR · 2025 survey
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR
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