2-Oleamido-1,3-Octadecanediol

2-Oleamido-1,3-Octadecanediol molecular structure
molecular structure · PubChem
AKA: 54422-45-6, MEXANYL GZ, 9-Octadecenamide, 3-OCTADECANEDIOL [INCI], (Z)-N-(1, 3-dihydroxyoctadecan-2-yl)octadec-9-enamide
Synthetic
Skin Conditioner
Clean
2-(9-(Z)-Octadecenylamido)-1,3-octadecanediol
Formula
C36H71NO3
Mol. Weight
566.00
CAS #
54422-45-6
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
A synthetic emulsifier and conditioning agent developed in the late 20th century. Derived from oleic acid (found in olive oil and other plant oils) and engineered for cosmetic formulations.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
ewg-1
medical-approval
pregnancy-nursing-safe
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Skin Types
●all-skin-types, gentle
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR