OriginSynthesized from phenylenediamine compounds and ethylene oxide derivatives through organic synthesis methods. Produced via nucleophilic substitution and hydrogenation reactions to form the stable hydrochloride salt.
2-(2,4-diaminophenoxy)ethanol dihydrochloride
Formula
C8H13ClN2O2
Mol. Weight
204.65
CAS #
66422-95-5
Form
Liquid
State
Solid; [MSDSonline] Light grey to light pink solid; [EC]
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
No
Functions
Hair Dyeing
Colors Hair
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
6
CIR
Safe as used
Pregnancy
No
CIR Safety Findings
Mixed Eye Irritation Results
4 studies / 1 irritating / 1 mixed / 2 not irritating / reactions slight (CIR 127 and 520 and 919)
Mixed Skin Irritation Results
3 studies / 1 irritating / 1 mixed / 1 not irritating / reactions slight (CIR 127 and 520 and 919)
Mixed Sensitization Results
3 studies / 2 sensitizing / 1 not sensitizing / plus 1 case report (CIR 127 and 520 and 919)
Dermal Absorption 0.03–0.75%
2 results from in vitro tests in the CIR safety assessment (CIR 520)
murphy