murphy3-Methylamino-4-Nitrophenoxyethanol
AKA: IMEXINE FR, 2-[3-(methylamino)-4-nitrophenoxy]ethanol, 59820-63-2, 2-(3-(Methylamino)-4-nitrophenoxy)ethanol
Synthetic
Not Clean
OriginSynthesized from nitrophenol and aminoethanol precursors through organic chemical synthesis methods. Produced via nucleophilic substitution reactions to introduce the methylamino group onto the nitrophenoxy backbone.
2-[3-(methylamino)-4-nitrophenoxy]ethanol
Formula
C9H12N2O4
Mol. Weight
212.20
CAS #
59820-63-2
Form
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
No
Functions
Hair Dyeing
Colors Hair
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
No
CIR Safety Findings
Not a Skin Irritant
1 study / 1 not irritating (CIR 451)
Not a Sensitizer
1 study / 1 not sensitizing (CIR 451)
Eye Irritant in Testing
1 study / 1 irritating / reactions slight (CIR 451)
Dermal Absorption 0.42%
human skin from 4 female donors / dermatomed ~400 µm / frozen/thawed / in vitro flow-through diffusion cells (0.61 cm2) / [14C] test substance 0.17% (w/w) in solvent-mix (55.5% hexylene glycol / 44.5% propylene glycol) / 12.8 mg (20 mg/cm2) applied for 30 min then washed / 24 h (CIR 451)
Concentration Guide
0%50%100%
Reg. limit 15%
EU regulatory limit: 15%. 0 Source: EU Cosmetics Regulation (EC) 1223/2009, Annex III (Restricted Substances), Entry 235.
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR