OriginSynthesized from p-aminophenol through nitration and oxidation reactions in laboratory settings. Produced by introducing a nitro group and hydroxyethyl substituent onto the aminophenol core structure.
4-[(2-hydroxyethyl)amino]-3-nitrophenol
Formula
C8H10N2O4
Mol. Weight
198.18
CAS #
65235-31-6
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
No
Functions
Hair Dyeing
Colors Hair
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
2 studies / 1 sensitizing / 1 not sensitizing / plus 1 case report (CIR 352)
Dermal Absorption 0.03–0.12%
2 results from in vitro tests in the CIR safety assessment (CIR 352)
Concentration Guide
0%50%100%
Reg. limit 1.85%
EU regulatory limit: 1.85%. 1.85 %. For (a) and (b): Hair colourants can use severe allergic reactions Read and follow intructions Source: EU Cosmetics Regulation (EC) 1223/2009, Annex III (Restricted Substances), Entry 248
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