4-Amino-3-Nitrophenol

AKA: 610-81-1, 3-Nitro-4-aminophenol, 2-Nitro-4-hydroxyaniline, 2-amino-5-hydroxynitrobenzene
Synthetic
Not Clean
OriginSynthesized from nitrobenzene derivatives through organic chemistry reactions involving aromatic compounds. Produced by nitration of aminophenol precursors followed by reduction and purification steps.
4-amino-3-nitrophenol
Formula
C6H6N2O3
Mol. Weight
154.12
CAS #
610-81-1
Form
Powder
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
No
Functions
Hair Dyeing
Locks In Moisture
Reduces Inflammation
Colors Hair
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
5
CIR
Safe as used
Pregnancy
No
CIR Safety Findings
Not a Skin Irritant
2 studies / 2 not irritating (CIR 352)
Mixed Eye Irritation Results
2 studies / 1 irritating / 1 not irritating (CIR 352)
Mixed Sensitization Results
2 studies / 1 sensitizing / 1 not sensitizing / plus 2 case reports (CIR 352)
Dermal Absorption 0.23–0.59%
2 results from in vitro tests in the CIR safety assessment (CIR 352)
Concentration Guide
0%50%100%
Reg. limit 1%
EU regulatory limit: 1.0%. (a) and (b) “ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos m... Source: EU Cosmetics Regulation (EC) 1223/2009, Annex III (Restricted Substances), Entry 215
Regulatory Status
USA✔ permitted
EU✔ permitted
JAPAN✔ permitted
CANADA✔ permitted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR