murphy4-Chloro-2-Aminophenol
AKA: 2-Amino-4-chlorophenol, 95-85-2, 5-CHLORO-2-HYDROXYANILINE, Fouramine PY, 2-Hydroxy-5-chloroaniline, P-Chloro-o-aminophenol, C.I. Oxidation Base 18, C.I. 76525
Synthetic
Not Clean
OriginSynthesized from 4-chloroaniline and phenol through chemical coupling and chlorination reactions in industrial synthesis. Produced via nucleophilic aromatic substitution followed by reduction to introduce the amino group.
The CIR Expert Panel concludes that the available data support the safety of 6-Amino-m-Cresol, 4-Amino-m-Cresol, 5-Amino-4-Chloro-o-Cresol and 5-Amino-6-Chloro-o-Cresol as used in oxidative and nonoxidative (semipermanent) for dyes. The available data also support the safety of 6-Amino-o-Cresol and 4-Chloro-2-Aminophenol for use in oxidative hair dyes, but are insufficient to support the safety of 6-Amino-o-Cresol and 4-Chloro-2-Aminophenol and nonoxidative (semipermanent) hair dyes.
Solubility less than 1 mg/mL at 68 °F (NTP, 1992)
Formula
C6H6ClNO
Mol. Weight
143.57
CAS #
95-85-2
Form
Powder
State
2-Amino-4-chlorophenol is a light brown colored crystalline solid. It may be toxic by ingestion. It is insoluble in water. It is used to make other chemicals.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
No
Functions
Hair Dyeing
Colors Hair
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory0 listings
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
3
CIR
Unsafe
Pregnancy
No
CIR Safety Findings
Sensitizer in Testing
1 study / 1 sensitizing / plus 1 case report (CIR 910)
Concentration Guide
CIR lists it as not reported to be in use.
CIR · 2021 survey
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR