4-Hydroxypropylamino-3-Nitrophenol

AKA: 92952-81-3, 4-[(3-Hydroxypropyl)amino]-3-nitrophenol, 4-((3-Hydroxypropyl)amino)-3-nitrophenol, Colorex RBN, Rot BN, Plakatrot Z, Covariane Rouge W 3127, HC Red BN
Synthetic
Not Clean
OriginSynthesized from nitrophenol precursors and aliphatic amine compounds through organic chemistry reactions. Produced via nitration and subsequent reduction or amination of phenolic intermediates.
1-Hydroxy-3-nitro-4-(3-hydroxypropylamino)benzene
Formula
C9H12N2O4
Mol. Weight
212.20
CAS #
92952-81-3
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
No
Functions
Hair Dyeing
Colors Hair
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
5
CIR
Safe as used
Pregnancy
No
CIR Safety Findings
Not a Skin Irritant
1 study / 1 not irritating (CIR 352)
Not a Sensitizer
1 study / 1 not sensitizing (CIR 352)
Eye Irritant in Testing
1 study / 1 irritating / reactions minimal (CIR 352)
Dermal Absorption 0.27%
Sprague-Dawley rats / in vivo / formulation with 1.5% 14C-ring-labeled ingredient / 30 minute exposure (CIR 352)
Concentration Guide
0%50%100%
Reg. limit 2.6%
EU regulatory limit: 2.6%. (a) To be printed on the label: The mixing ratio. “ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of... Source: EU Cosmetics Regulation (EC) 1223/2009, Annex III (Restricted Substances), Entry 205
Regulatory Status
USA✔ permitted
EU✔ permitted
JAPAN✔ permitted
CANADA✔ permitted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR