murphy4-Methoxy-m-Phenylenediamine
AKA: 2, 4-DIAMINOANISOLE, 615-05-4, Pelagol L, Pelagol DA, Pelagol Grey L, Furro L, 4-Diaminoanisol, M-Diaminoanisole, 1, 3-Benzenediamine
Synthetic
Not Clean
OriginSynthesized from m-phenylenediamine and methanol through chemical oxidation and methylation reactions. Produced via controlled coupling and substitution processes to form the stable aromatic amine compound.
On the basis of the information included in this report the CIR Expert Panel concludes that 4-Methoxy-m-Phenylenediamine, 4-Methoxy-m-Phenylenediamine Sulfate and 4-Methoxy-m-Phenylenediamine HCL are unsafe for use in cosmetic products.
Solubility Soluble in alcohol, hot ether; slightly soluble in DMSO
Formula
C7H10N2O
Mol. Weight
138.17
CAS #
615-05-4
Form
Liquid
State
2,4-diaminoanisole appears as colorless needles. Primarily used (along with salts such as 2,4-diaminoanisole sulfate) as a component of hair & fur dye formulations. (NIOSH, 2024)
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
No
Allergen Warning
⚠️ PPD (Hair Dye)
Functions
Hair Dyeing
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory0 listings
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
No
CIR Safety Findings
Not an Eye Irritant
1 study / 1 not irritating (CIR 99)
Skin Irritant in Testing
1 study / 1 irritating / reactions mild (CIR 99)
Dermal Absorption 0.0021–1.5%
12 results from animal / human tests in the CIR safety assessment (CIR 99)
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR