5-Amino-4-Chloro-o-Cresol

5-Amino-4-Chloro-o-Cresol 1
molecular structure · PubChem CID 10176241
AKA: 110102-86-8, Phenol, 2-Methyl-4-chloro-5-aminophenol, 2-Methyl-5-amino-4-chlorophenol, 3-Amino-4-chloro-6-methylphenol, 5-Amino-4-chloro-o-cresol [INCI]
Synthetic
Not Clean
OriginSynthesized from o-cresol and chlorine-based precursors through chlorination and amination reactions. Produced via multi-step organic synthesis involving electrophilic aromatic substitution and reduction processes.
5-Amino-4-chloro-2-methylphenol
Formula
C7H8ClNO
Mol. Weight
157.60
CAS #
110102-86-8
Form
Powder
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
No
Functions
Hair Dyeing
Colors Hair
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
No
CIR Safety Findings
Eye Irritant in Testing
1 study / 1 irritating / reactions slight (CIR 276)
Mixed Skin Irritation Results
3 studies / 1 irritating / 2 not irritating / reactions slight (CIR 276)
Mixed Sensitization Results
2 studies / 1 sensitizing / 1 not sensitizing / reactions moderate (CIR 276 and 877)
Dermal Absorption 1.28–32.7%
2 results from animal tests in the CIR safety assessment (CIR 276)
Concentration Guide
CIR lists it as not reported to be in use.
CIR · report published 2023
Regulatory Status
USA✔ permitted
EU✔ permitted
JAPAN✔ permitted
CANADA✔ permitted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR