5-Amino-4-Chloro-o-Cresol HCl

5-Amino-4-Chloro-o-Cresol HCl 1
molecular structure · PubChem CID 22153846
AKA: 110102-85-7, 5-Amino-4-chloro-o-cresol hydrochloride, Phenol, Hydrochloride, 2-Methyl-4-chloro-5-aminophenol hydrochloride, 5-Amino-4-chloro-o-cresol HCl [INCI], Hydrochloride (1:1)
Synthetic
Not Clean
Origin5-Amino-4-Chloro-o-Cresol HCl is synthesized from o-cresol, a methylphenol derived from petroleum or coal tar sources. The compound is produced through chlorination and amination reactions, followed by hydrochloride salt formation.
5-Amino-4-chloro-2-methylphenol hydrochloride
Formula
C7H9Cl2NO
Mol. Weight
194.06
CAS #
110102-85-7
Form
Powder
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
No
Functions
Hair Dyeing
Colors Hair
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
No
CIR Safety Findings
Mixed Skin Irritation Results
4 studies / 1 irritating / 3 not irritating / reactions slight (CIR 877)
Mixed Sensitization Results
3 studies / 1 sensitizing / 2 not sensitizing (CIR 877)
Eye Irritant in Testing
3 studies / 3 irritating / reactions slight to severe (CIR 877)
Dermal Absorption 1.28–32.7%
3 animal and lab (in vitro) studies in the CIR safety assessment (CIR 877)
Concentration Guide
CIR lists it as not reported to be in use.
CIR · report published 2023
Regulatory Status
USA✔ permitted
EU✔ permitted
JAPAN✔ permitted
CANADA✔ permitted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR