murphy5-Bromo-5-Nitro-1,3-Dioxane
AKA: 30007-47-7, Bronidox, 5-Bromo-5-nitro-m-dioxane, M-DIOXANE, 5-Brom-5-nitro-1, MICROCIDE I
Synthetic
Preservative
Not Clean
OriginSynthesized from 1,3-dioxane, a six-membered cyclic ether compound, through organic chemistry reactions. Produced by introducing bromine and nitro functional groups onto the dioxane ring structure.
Bronidox is an organobromide that is a nitrobromo derivative of dioxane. It is used as a stabilizer, surfacant, bactericide, and a preservative in immunology and cosmetics. It is corrosive to metals. Bronidox has been used in cosmetics since the mid-1970s as preservative for shampoos and foam baths.
Formula
C4H6BrNO4
Mol. Weight
212.00
CAS #
30007-47-7
Form
Powder
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Functions
Preservative
Keeps your product from growing bacteria, mold, or yeast. Without these, that jar of cream becomes a petri dish in about a week.
Preserves Formula
Prevents microbial growth
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Not a Sensitizer
2 studies / 2 not sensitizing / plus 1 case report (CIR 140)
Not Phototoxic
Animal test found no phototoxicity in the CIR safety assessment (CIR 140)
Mixed Eye Irritation Results
1 study / 1 mixed / reactions strong (CIR 140)
Mixed Skin Irritation Results
4 studies / 1 irritating / 2 mixed / 1 not irritating (CIR 140)
Dermal Absorption 7–75.3%
3 results from animal / human tests in the CIR safety assessment (CIR 140)
Concentration Guide
0%50%100%
Reg. limit 0.1%
EU regulatory limit: 0.1%. Source: EU Cosmetics Regulation (EC) 1223/2009, Annex V (Preservatives), Entry 20.
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR