murphy6-Hydroxyindole
AKA: 2380-86-1, 1H-indol-6-ol, IMEXINE OBA, 417-020-4, 6-indolol
Synthetic
Not Clean
Origin6-Hydroxyindole is synthesized from indole, an organic compound derived from coal tar or petroleum-based chemical precursors. It is produced through hydroxylation of indole using oxidation reactions or catalytic chemical processes.
structure in first source
Formula
C8H7NO
Mol. Weight
133.15
CAS #
2380-86-1
Form
Powder
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Functions
Hair Dyeing
Colors Hair
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
7
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Mixed Phototoxicity Results
Both phototoxic and non-phototoxic results in the CIR safety assessment (CIR 635)
Mixed Skin Irritation Results
4 studies / 3 irritating / 1 not irritating / reactions slight to moderate (CIR 635)
Mixed Sensitization Results
7 studies / 6 sensitizing / 1 mixed (CIR 635)
Mixed Eye Irritation Results
2 studies / 1 irritating / 1 not irritating / reactions moderate to severe (CIR 635)
Dermal Absorption 1.94–5.6%
3 animal and lab (in vitro) studies in the CIR safety assessment (CIR 635)
Regulatory Agencies
🧂Conflict of interest.
Verified Jun 2026 · 🧪 = conflict
Data: PubChem · CosIng · EWG · CIR