Acetyl Glutamic Acid

AKA: N-Acetyl-L-glutamic acid, 1188-37-0, Acetylglutamic acid, N-acetyl-L-glutamate, Acetyl-L-glutamic acid, N-Acetylglutamate, (2S)-2-acetamidopentanedioic acid, Ac-Glu-OH, L-N-Acetylglutamic acid
Synthetic
Skin Conditioner
Acid
Not Clean
OriginDerived from glutamic acid, a naturally occurring amino acid, through synthetic acetylation processes. Synthesized by acetylating glutamic acid with acetic anhydride or similar acetylating agents.
The panel concluded that the 115 amino acid alkyl amides listed below are safe in the present practices of use and concentration in cosmetics, when formulated to be non-irritating...Acetyl Glutamic Acid
Solubility 52 mg/mL
Formula
C7H11NO5
Mol. Weight
189.17
CAS #
1188-37-0
Form
Liquid
State
Solid
Skin Types
●all-skin-types
Best For
Dehydration
Pregnancy & Breastfeeding Safe
Yes
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Yes
Concentration Guide
CIR lists it as not reported to be in use.
CIR · report published 2017
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR